Peptide Interactions intermediate
Amyloid-beta → Neprilysin (Substrate)
Comprehensive reference for Amyloid-beta → Neprilysin (Substrate), a peptide compound with applications in research and therapeutics.
By Encyclopeptide Editorial | 1 min read
peptide-interactions peptide oligopeptide
Overview
Amyloid-beta → Neprilysin (Substrate) is a bioactive peptide with well-characterized properties and therapeutic applications.
Mechanism of Action
Neprilysin (Zn2+ metalloprotease) cleaves Aβ at multiple sites including His14-Gln15, Phe19-Phe20, and other hydrophobic residues, generating non-amyloidogenic fragments. NEP is the dominant Aβ-degrading enzyme in brain.
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
Chemical Identity
| Property | Value |
|---|---|
| Name | Amyloid-beta → Neprilysin (Substrate) |
| Category | Peptide Interactions |
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