ALS: Oligopeptide Research Reference
Progressive motor neuron disease affecting both upper (cortical) and lower (spinal) motor neurons. Sporadic (90%) or familial (10%, SOD1, C9orf72, TARDBP, FU...
Overview
Progressive motor neuron disease affecting both upper (cortical) and lower (spinal) motor neurons. Sporadic (90%) or familial (10%, SOD1, C9orf72, TARDBP, FU…ess, atrophy, fasciculations, spasticity. Mean survival 3-5 years from diagnosis. Treatments: riluzole (extends survival 2-3 months), edaravone (slows decline), tofersen (SOD1 mutations), sodium phenylbutyrate/taurursodiol.
Clinical Significance
This molecule has important therapeutic or diagnostic applications in clinical medicine.
References
- Encyclopeptide Database. “ALS” monograph. encyclopeptide.com.
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