Antimicrobial Peptides intermediate
Antimicrobial Peptide Drugs: Comprehensive Peptide Reference
Therapeutic antimicrobial peptides for drug-resistant infections including cationic and lipopeptide classes. This peptide or oligopeptide is studied for its ...
By Encyclopeptide Editorial | 1 min read
antimicrobial AMP drug-resistant cationic-peptide lipopeptide
Approved AMP Drugs
| Drug | Class | Target | Spectrum |
|---|---|---|---|
| Daptomycin | Lipopeptide | Cell membrane | Gram-positive |
| Polymyxin B | Lipopeptide | Cell membrane | Gram-negative |
| Colistin | Lipopeptide | Cell membrane | Gram-negative |
| Nisin | Lantibiotic | Cell wall | Gram-positive |
Mechanism of Action
Cationic AMPs
- Electrostatic attraction to anionic bacterial membranes
- Membrane disruption and pore formation
- Intracellular targets (DNA, protein synthesis)
Lipopeptides
- Calcium-dependent membrane insertion
- Ion channel formation
- Membrane depolarization
Chemical Identity
| Property | Value |
|---|---|
| Name | Antimicrobial Peptide Drugs |
| Category | Antimicrobial Peptides |
References
- Encyclopeptide Database. “Antimicrobial Peptide Drugs” monograph. encyclopeptide.com.
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