Insect Peptides intermediate
Apamin (Apis): Oligopeptide Research Reference
Apamin (Apis), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
insect-peptides peptide oligopeptide
Overview
Apamin (Apis) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Apis mellifera (honeybee).
Structure
| Property | Value |
|---|---|
| Name | Apamin (Apis) |
| Sequence | CNCKAPETALCARRCQQH |
| Length | 18 amino acids |
| Molecular Weight | 2027 Da |
| Source | Apis mellifera (honeybee) |
| Category | Venom Peptide / KCa2.x Blocker |
Mechanism of Action
Selective blocker of KCa2.1, KCa2.2, and KCa2.3 channels, crosses blood-brain barrier
Bioactivity
Neurotoxin, induces hyperexcitability, memory-enhancing properties
Therapeutic Potential
Cognitive enhancement, neurodegenerative diseases, pain research tool
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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