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Therapeutic Peptides Expanded intermediate

Colistimethate: Oligopeptide Research Reference

Colistimethate, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development

By Encyclopeptide Editorial | 1 min read
therapeutic-peptides-expanded peptide oligopeptide

Overview

Colistimethate is a bioactive peptide with well-characterized properties and therapeutic applications.

Structure

PropertyValue
NameColistimethate
SequenceMethanesulfonated polymyxin E: fatty acyl-Thr-Leu-Leu-Ser-Dab-Dab-Dab-D-Leu-Dab-Dab
Length10 amino acids (polymyxin prodrug)
Molecular Weight1750 Da (sodium form)

| Category | Anti-Infective / Polymyxin Antibiotic |

Mechanism of Action

Prodrug converted to colistin; disrupts bacterial outer membrane via LPS binding

References

  • Wikipept Peptide Database
  • Primary literature (see individual entries)

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