Cyclosporin A: Oligopeptide Research Reference
Cyclosporin A, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
Overview
Cyclosporin A is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Tolypocladium inflatum.
Structure
| Property | Value |
|---|---|
| Name | Cyclosporin A |
| Length | 11 amino acids | | Molecular Weight | 1202.61 Da | | Source | Tolypocladium inflatum | | Category | Fungal Antibiotic / Immunosuppressant |
Mechanism of Action
Binds cyclophilin forming complex that inhibits calcineurin phosphatase; blocks T-cell activation and IL-2 transcription
Bioactivity
Immunosuppressant, anti-inflammatory
Therapeutic Potential
Organ transplant rejection prevention, autoimmune diseases (psoriasis, rheumatoid arthritis)
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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