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Antimicrobial Peptides intermediate

Defensin human alpha: Structure, Function, and Significance

Human alpha-defensins (HNP1-4) are 29-30 residue antimicrobial peptides stored in neutrophil azurophilic granules. They form pores in microbial membranes.

By Encyclopeptide Editorial | 1 min read
defensin-human-alpha alpha-defensin antimicrobial-peptides human-neutrophils

Chemical Identity

PropertyValue
Peptide Namedefensin-human-alpha
TypeAlpha-defensin
SourceHuman neutrophils
SequenceDCYNCIPSSGPRHSRGICSLIFCR
Molecular Weight2708.3 Da

Description

Human alpha-defensins (HNP1-4) are 29-30 residue antimicrobial peptides stored in neutrophil azurophilic granules. They form pores in microbial membranes.

Biological Function

Human alpha-defensins (HNP1-4) are 29-30 residue antimicrobial peptides stored in neutrophil azurophilic granules. They form pores in microbial membranes.

Research Significance

This alpha-defensin has been studied for its potential applications in:

  • Drug development
  • Biotechnology
  • Biomaterials
  • Therapeutics

References

  1. Encyclopeptide Database. “defensin-human-alpha” monograph. encyclopeptide.com.

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