Amphibian Peptides intermediate
Dermorphin: Antimicrobial Peptide Reference
Dermorphin, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
amphibian-peptides peptide oligopeptide
Overview
Dermorphin is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Phyllomedusa sauvagei (Sauvage’s leaf frog).
Structure
| Property | Value |
|---|---|
| Name | Dermorphin |
| Sequence | YAFGYPS-NH2 |
| Length | 7 amino acids |
| Molecular Weight | 803.9 Da |
| Source | Phyllomedusa sauvagei (Sauvage’s leaf frog) |
| Category | Amphibian Opioid |
Mechanism of Action
Highly selective MOR agonist, contains D-alanine residue conferring resistance to proteases
Bioactivity
Extremely potent analgesic (1000x morphine), opioid effects
Therapeutic Potential
Pain management, opioid pharmacology research, analgesic drug development
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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