Skip to content
Peptide Families advanced

Epidermal Growth Factor Family

Learn about EGF, TGF-alpha, and amphiregulin in epithelial growth and cancer biology.

By Encyclopeptide Editorial | 1 min read
egf growth-factor epithelial peptide-family

Overview

EGF Family Peptides bind ErbB receptors and regulate epithelial growth, differentiation, and survival.

Key Members

  • EGF: Prototype growth factor binding EGFR
  • TGF-alpha: Autocrine growth factor
  • Amphiregulin: EGFR ligand in immune regulation
  • Betacellulin: Pancreatic beta cell growth
  • Neuregulins: Neural and cardiac development

Clinical Significance

EGFR-targeting therapies (cetuximab, erlotinib) are cornerstone cancer treatments.

References

  • Source: ENCP Peptide Database
  • Category: Peptide Families

Test Your Knowledge

Reinforce what you learned about Epidermal Growth Factor Family with interactive quizzes on Wikipept.

Take a Quiz on Wikipept