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Endothelin Family Peptides
Guide to endothelin peptides ET-1, ET-2, ET-3 in vasoconstriction and cardiovascular regulation.
By Encyclopeptide Editorial | 1 min read
endothelin vasoconstriction cardiovascular peptide-family
Overview
Endothelin Family Peptides are 21-amino acid peptides with potent vasoconstrictive properties.
Key Members
- ET-1: Most potent endogenous vasoconstrictor
- ET-2: Similar potency to ET-1
- ET-3: Distinct receptor selectivity
- Sarafotoxin: Snake venom homolog
Clinical Significance
Endothelin receptor antagonists (bosentan, ambrisentan) treat pulmonary arterial hypertension.
References
- Source: ENCP Peptide Database
- Category: Peptide Families
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