Overview

Neuronal hyperexcitability causing recurrent unprovoked seizures. Classification: focal (partial) or generalized. Etiology: idiopathic (genetic, 60%), sympto…nic (10%). Electroencephalography: epileptiform discharges. Treatments: antiepileptic drugs (carbamazepine, valproate, lamotrigine, levetiracetam, topiramate). Drug-resistant epilepsy (20-30%): vagus nerve stimulation, responsive neurostimulation, ketogenic diet, resective surgery.

Clinical Significance

This molecule has important therapeutic or diagnostic applications in clinical medicine.

References

1. Encyclopeptide Database. “Epilepsy” monograph. encyclopeptide.com.