Ergotamine: Oligopeptide Research Reference
Ergotamine, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
Overview
Ergotamine is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Claviceps purpurea.
Structure
| Property | Value |
|---|---|
| Name | Ergotamine |
| Length | 3 amino acids (peptide portion) | | Molecular Weight | 581.66 Da | | Source | Claviceps purpurea | | Category | Fungal Cyclopeptide / Alkaloid |
Mechanism of Action
Serotonin antagonist and partial agonist; causes vasoconstriction through alpha-adrenergic activation
Bioactivity
Vasoconstrictor, antimigraine
Therapeutic Potential
Migraine treatment (combined with caffeine); historically important antimigraine drug
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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