Therapeutic Peptides Expanded 2 intermediate
Eteplirsen: Oligopeptide Research Reference
Eteplirsen, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
therapeutic-peptides-expanded-2 peptide oligopeptide
Overview
Eteplirsen is a bioactive peptide with well-characterized properties and therapeutic applications.
Structure
| Property | Value |
|---|---|
| Name | Eteplirsen |
| Sequence | Phosphorodiamidate morpholino oligomer (PMO), 30-mer antisense oligonucleotide |
| Length | 30 nucleotides (morpholino chemistry) |
| Molecular Weight | ~10.3 kDa |
| Category | Rare Disease / Antisense Oligonucleotide |
Mechanism of Action
Antisense oligonucleotide binds exon 51 of dystrophin pre-mRNA, inducing exon skipping during splicing to restore the reading frame and produce truncated dystrophin
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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