GLP-1 Family intermediate
Exenatide Once Weekly
Extended-release microsphere formulation of exenatide providing sustained GLP-1 receptor agonism with once-weekly dosing.
By Encyclopeptide Editorial | 1 min read
exenatide extended-release microspheres once-weekly GLP-1
Chemical Identity
| Property | Value |
|---|---|
| Product Name | Bydureon |
| Formulation | PLGA microspheres |
| Dose | 2 mg once weekly |
Structure
Bydureon encapsulates exenatide in PLGA microspheres that slowly degrade in subcutaneous tissue, releasing exenatide over one week.
Pharmacokinetics
- Tmax: 2-3 hours (initial), sustained over 7 days
- Half-life: ~5 days (effective)
- Steady state: 2-4 weeks
Biological Significance
This molecule plays important roles in biological systems and has potential therapeutic applications.
References
- Encyclopeptide Database. “Exenatide Once Weekly” monograph. encyclopeptide.com.
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