Fumitremorgin C: Oligopeptide Research Reference
Fumitremorgin C, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
Overview
Fumitremorgin C is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Aspergillus fumigatus.
Structure
| Property | Value |
|---|---|
| Name | Fumitremorgin C |
| Length | 2 amino acids (diketopiperazine core) | | Molecular Weight | 379.47 Da | | Source | Aspergillus fumigatus | | Category | Fungal Cyclopeptide / Chemosensitizer |
Mechanism of Action
Specific inhibitor of ABCG2/BCRP efflux pump; reverses multidrug resistance in cancer cells
Bioactivity
Chemosensitizer, reverses drug resistance
Therapeutic Potential
Adjuvant cancer therapy to overcome multidrug resistance; Ko145 analog in clinical trials
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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