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Peptide Interactions intermediate

GIP → DPP-4 (Substrate): Oligopeptide Research Reference

GIP → DPP-4 (Substrate), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development

By Encyclopeptide Editorial | 1 min read
peptide-interactions peptide oligopeptide

Overview

GIP → DPP-4 (Substrate) is a bioactive peptide with well-characterized properties and therapeutic applications.

Mechanism of Action

DPP-4 cleaves N-terminal Tyr1-Ala2 dipeptide from GIP, producing GIP (3-42) which has greatly reduced receptor binding affinity. GIP normally acts via GIPR (class B GPCR) to stimulate insulin secretion in a glucose-dependent manner.

References

  • Wikipept Peptide Database
  • Primary literature (see individual entries)

Chemical Identity

PropertyValue
NameGIP → DPP-4 (Substrate)
CategoryPeptide Interactions

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