Gliotoxin: Oligopeptide Research Reference
Gliotoxin, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
Overview
Gliotoxin is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Aspergillus fumigatus.
Structure
| Property | Value |
|---|---|
| Name | Gliotoxin |
| Length | 2 amino acids (diketopiperazine core) | | Molecular Weight | 326.37 Da | | Source | Aspergillus fumigatus | | Category | Fungal Cyclopeptide / Toxin |
Mechanism of Action
Inhibits NF-kB by preventing I-kB degradation; generates reactive oxygen species; induces apoptosis
Bioactivity
Immunosuppressive, anti-inflammatory, pro-apoptotic
Therapeutic Potential
Autoimmune disease therapy; anti-inflammatory drug development; antifungal virulence factor research
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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