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Worm Peptides intermediate

Hirudin HV1: Oligopeptide Research Reference

Hirudin HV1, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development

By Encyclopeptide Editorial | 1 min read
worm-peptides peptide oligopeptide

Overview

Hirudin HV1 is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Hirudo medicinalis (medicinal leech).

Structure

PropertyValue
NameHirudin HV1
SequenceVVYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPKPQSHNDGDFEEIPEEYLQ
Length65 amino acids
Molecular Weight6960 Da
SourceHirudo medicinalis (medicinal leech)
CategoryLeech Thrombin Inhibitor

Mechanism of Action

Bivalent thrombin inhibitor, N-terminal domain blocks active site, C-terminal binds exosite I

Bioactivity

Anticoagulant, prevents platelet aggregation and fibrin formation

Therapeutic Potential

Parenteral anticoagulant, heparin-induced thrombocytopenia treatment

References

  • Wikipept Peptide Database
  • Primary literature (see individual entries)

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