Peptide History intermediate
History of Peptide Biomarker Development
How peptide biomarkers were discovered and validated for clinical diagnostics.
By Encyclopeptide Editorial | 1 min read
biomarkers diagnostics clinical history
Overview
Peptide biomarkers have transformed clinical diagnostics, enabling detection and monitoring of numerous diseases.
Key Milestones
- 1959: RIA for insulin measurement
- 1970s: Troponin as cardiac marker
- 1980s: PSA for prostate cancer screening
- 1990s: BNP for heart failure
- 2000s: Procalcitonin for sepsis
- 2010s: Amyloid-beta and tau for Alzheimer’s
Impact
Peptide biomarkers guide clinical decisions in cardiology, oncology, infectious disease, and neurology.
Validation
Rigorous analytical and clinical validation ensures biomarker reliability for clinical use.
References
- Source: ENCP Peptide Database
- Category: Peptide History
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