Peptide History beginner
History of Peptide Therapeutics
From insulin to modern GLP-1 agonists, the evolution of peptide drugs over a century.
By Encyclopeptide Editorial | 1 min read
therapeutics drugs history clinical
Overview
Peptide therapeutics have grown from early insulin preparations to a diverse class of drugs treating diabetes, cancer, rare diseases, and more.
Key Milestones
- 1922: First insulin injection
- 1970s: GnRH agonists for cancer
- 1980s: Cyclosporine for transplant rejection
- 1990s: Enfuvirtide for HIV
- 2000s: Exenatide for type 2 diabetes
- 2010s: GLP-1 agonists transform obesity treatment
- 2020s: Peptide drug conjugates and stapled peptides
Impact
Over 80 peptide drugs are now approved worldwide, with the market exceeding $50 billion annually. Peptides bridge the gap between small molecules and biologics.
References
- Source: ENCP Peptide Database
- Category: Peptide History
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