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Inhibin and Activin Family Peptides

Guide to inhibin and activin peptides in TGF-beta signaling and reproductive biology.

By Encyclopeptide Editorial | 1 min read
inhibin activin tgf-beta peptide-family

Overview

Inhibin and Activin Family Peptides are TGF-beta superfamily members regulating FSH secretion and cell differentiation.

Key Members

  • Inhibin A/B: Suppress FSH secretion
  • Activin A/B: Stimulate FSH secretion
  • GDF9/BMP15: Oocyte-specific growth factors
  • Follistatin: Activin-binding protein

Clinical Significance

Activin A is a biomarker for several cancers; follistatin-based therapeutics are in clinical trials for muscle wasting.

References

  • Source: ENCP Peptide Database
  • Category: Peptide Families

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