GLP-1 Family intermediate
Lixisenatide Once Daily
Short-acting GLP-1 receptor agonist with rapid onset and short duration, primarily targeting postprandial glucose excursions.
By Encyclopeptide Editorial | 1 min read
lixisenatide GLP-1 once-daily postprandial diabetes
Chemical Identity
| Property | Value |
|---|---|
| Chemical Formula | C215H342N60O66S |
| Molecular Weight | 4858.59 g/mol |
| CAS Number | 851729-34-3 |
| Product Name | Lyxumia (EU), Adlyxin (US) |
Structure
Lixisenatide is a 33-amino acid exendin-4 analog with deletion of Pro38 and Pro39, and addition of six lysine residues at the C-terminus.
Pharmacokinetics
- Half-life: 2-4 hours
- Onset: 30 minutes
- Peak: 1-2 hours
- Duration: 6-8 hours
- Dosing: Once daily within 1 hour before the first meal
Biological Significance
This molecule plays important roles in biological systems and has potential therapeutic applications.
References
- Encyclopeptide Database. “Lixisenatide Once Daily” monograph. encyclopeptide.com.
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