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Peptide Families intermediate

Melanocortin Family Peptides

Learn about alpha-MSH, beta-MSH, and ACTH in pigmentation, energy balance, and inflammation.

By Encyclopeptide Editorial | 1 min read
melanocortin msh pigmentation peptide-family

Overview

Melanocortin Family Peptides regulate pigmentation, energy balance, and inflammation through MC1-MC5 receptors.

Key Members

  • Alpha-MSH: Pigmentation and anti-inflammatory effects
  • Beta-MSH: Energy homeostasis
  • ACTH: Adrenal steroidogenesis
  • Gamma-MSH: Cardiovascular regulation

Clinical Significance

Setmelanotide is an MC4R agonist approved for genetic obesity. Afamelanotide treats erythropoietic protoporphyria.

References

  • Source: ENCP Peptide Database
  • Category: Peptide Families

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