Insect Peptides intermediate
Melittin (Apis): Oligopeptide Research Reference
Melittin (Apis), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
insect-peptides peptide oligopeptide
Overview
Melittin (Apis) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Apis mellifera (honeybee).
Structure
| Property | Value |
|---|---|
| Name | Melittin (Apis) |
| Sequence | GIGAVLKVLTTGLPALISWIKRKRQQ |
| Length | 26 amino acids |
| Molecular Weight | 2846 Da |
| Source | Apis mellifera (honeybee) |
| Category | Venom Peptide / Membrane Disruption |
Mechanism of Action
Pore-forming peptide, disrupts lipid bilayers via barrel-stave or toroidal pore mechanism
Bioactivity
Potent hemolytic, anti-inflammatory, antimicrobial, anticancer activities
Therapeutic Potential
Anti-cancer therapy (melittin-ADC conjugates), anti-inflammatory agents, antimicrobial coatings
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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