Peptide Modifications advanced
Peptide Methylation Sites
Learn about arginine and lysine methylation in peptide epigenetic regulation.
By Encyclopeptide Editorial | 1 min read
methylation epigenetics modification
Overview
Methylation adds methyl groups to arginine and lysine residues, regulating transcription and signal transduction.
Types
- Arginine methylation: Mono-, symmetric di-, or asymmetric di-methylation
- Lysine methylation: Mono-, di-, or tri-methylation
Biological Significance
Histone methylation marks (H3K4me3, H3K27me3, H3K9me3) define active and silent chromatin states. EZH2 inhibitors target aberrant methylation in cancer.
References
- Source: ENCP Peptide Database
- Category: Peptide Modifications
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