Peptide Modifications advanced
Peptide Myristoylation Sites: Comprehensive Peptide Refer...
Explore N-myristoylation in peptide membrane association and protein interactions. This modification affects peptide stability, receptor binding, and biologi...
By Encyclopeptide Editorial | 1 min read
myristoylation lipid membrane modification
Overview
N-myristoylation attaches myristate (C14) to N-terminal glycine residues via N-myristoyltransferase (NMT).
Characteristics
Co-translational modification occurring after methionine removal. Some cases are post-translational (caspase cleavage exposure).
Biological Significance
Myristoylation is essential for Src family kinase, Arf GTPase, and caspase membrane association. NMT inhibitors show anticancer potential.
References
- Source: ENCP Peptide Database
- Category: Peptide Modifications
Chemical Identity
| Property | Value |
|---|---|
| Name | Peptide Myristoylation Sites |
| Category | Peptide Modifications |
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