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Peptide Anticancer Agents: Comprehensive Peptide Reference

Learn about peptide-based anticancer strategies including targeted delivery and apoptosis induction. This peptide or oligopeptide is studied for its biologic...

By Encyclopeptide Editorial | 1 min read
anticancer oncology targeted-therapy application

Overview

Peptide-based anticancer agents exploit tumor-homing peptides, peptide-drug conjugates, and pro-apoptotic peptides for selective cancer therapy.

Strategies

  • Tumor-homing peptides: RGD, NGR motifs targeting tumor vasculature
  • Peptide-drug conjugates (PDCs): Targeted cytotoxic delivery
  • Pro-apoptotic peptides: Directly triggering tumor cell death
  • Checkpoint peptide modulators: Immune activation

Examples

Lutetium-177 DOTATATE (Lutathera) targets somatostatin receptors in neuroendocrine tumors. Melflufen is a peptide-drug conjugate for myeloma.

Clinical Significance

PDCs represent a growing drug class with advantages in tumor penetration and reduced off-target toxicity.

References

  • Source: ENCP Peptide Database
  • Category: Peptide Applications

Chemical Identity

PropertyValue
NamePeptide Anticancer Agents
CategoryPeptide Applications

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