Venom Peptides intermediate
Philanthotoxin: Peptide Toxin in Pharmacology Reference
Philanthotoxin, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
venom-peptides peptide oligopeptide
Overview
Philanthotoxin is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Philanthus triangulum (European beewolf wasp).
Structure
| Property | Value |
|---|---|
| Name | Philanthotoxin |
| Sequence | Polyamine toxin - spermine conjugated to tyrosine/phenylalanine derivatives |
| Length | Small molecule (polyamine conjugate) |
| Molecular Weight | 450-750 Da (analogs vary) |
| Source | Philanthus triangulum (European beewolf wasp) |
| Category | Venom Peptide / nAChR/Glutamate Blocker |
Mechanism of Action
Open-channel blocker of nAChRs and AMPA/kainate glutamate receptors
Bioactivity
Neurotoxin causing paralysis of prey (honeybees), anticonvulsant properties
Therapeutic Potential
Epilepsy treatment, neuroprotection, research tool for ion channel studies
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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