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Mammalian Peptides intermediate

Protegrin 1: Oligopeptide Research Reference

Protegrin 1, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development

By Encyclopeptide Editorial | 1 min read
mammalian-peptides peptide oligopeptide

Overview

Protegrin 1 is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Sus scrofa (Pig).

Structure

PropertyValue
NameProtegrin 1
SequenceRGGRLCYCRRRFCVCVGR
Length18 amino acids
Molecular Weight2221.7 Da
SourceSus scrofa (Pig)
CategoryPorcine Antimicrobial

Mechanism of Action

Beta-hairpin peptide with two disulfide bonds, forms transmembrane pores

Bioactivity

Potent broad-spectrum antimicrobial against bacteria, fungi, and HIV

Therapeutic Potential

Treatment of multidrug-resistant infections, anti-HIV therapeutics

References

  • Wikipept Peptide Database
  • Primary literature (see individual entries)

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