Insect Peptides intermediate
Prothoracicotropic Hormone (PTTH)
Comprehensive reference for Prothoracicotropic Hormone (PTTH), a peptide compound with applications in research and therapeutics.
By Encyclopeptide Editorial | 1 min read
insect-peptides peptide oligopeptide
Overview
Prothoracicotropic Hormone (PTTH) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Bombyx mori (silkworm), Manduca sexta.
Structure
| Property | Value |
|---|---|
| Name | Prothoracicotropic Hormone (PTTH) |
| Sequence | Homodimeric peptide, each subunit ~110 amino acids with disulfide bonds |
| Length | 224 amino acids (homodimer) |
| Molecular Weight | 25000 Da (homodimer) |
| Source | Bombyx mori (silkworm), Manduca sexta |
| Category | Insect Hormone / Development |
Mechanism of Action
Binds Torso receptor tyrosine kinase, stimulates ecdysone biosynthesis
Bioactivity
Initiates molting and metamorphosis via ecdysteroid synthesis
Therapeutic Potential
Pest control via developmental disruption, biotechnology research tool
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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