Therapeutic Peptides Expanded 2 intermediate
Sacituzumab Tirumotecan: Oligopeptide Research Reference
Sacituzumab Tirumotecan, a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
therapeutic-peptides-expanded-2 peptide oligopeptide
Overview
Sacituzumab Tirumotecan is a bioactive peptide with well-characterized properties and therapeutic applications.
Structure
| Property | Value |
|---|---|
| Name | Sacituzumab Tirumotecan |
| Sequence | Anti-Trop2 monoclonal antibody conjugated to belotecan-derived topoisomerase I inhibitor via novel cleavable linker |
| Length | ~1327 amino acids (antibody) + linker-payload |
| Molecular Weight | ~160 kDa (ADC) |
| Category | Oncology / Antibody-Drug Conjugate |
Mechanism of Action
ADC targeting Trop2; delivers belotecan-derived payload to Trop2-expressing tumor cells, causing DNA strand breaks and apoptosis
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
Test Your Knowledge
Reinforce what you learned about Sacituzumab Tirumotecan: Oligopeptide Research Reference with interactive quizzes on Wikipept.
Take a Quiz on Wikipept