**Sequence:** 439 amino acids (precursor processed to multiple fragments)

Overview

Sequence: 439 amino acids (precursor processed to multiple fragments) is a peptide compound with applications in research and therapeutics. Sequence: 237 amino acids (kallikrein-3, KLK3)

Chemical Identity

Property	Value
Name	Sequence: 439 amino acids (precursor processed to multiple fragments)
Sequence	Disease: Neuroendocrine tumors (NETs); pheochromocytoma; small cell lung cancer; carcinoid syndrome

Clinical Use: Screening/diagnosis of NETs; monitoring treatment response; recurrence detection; prognostic in heart failure

Cutoff Values: <100 ng/mL (normal, assay-dependent). Elevated: >300–400 ng/mL suggestive of NET. PPIs, renal failure, atrophic gastritis, and chronic HF can cause false elevations.

Most widely used circulating NET marker. Secreted by neuroendocrine cells and co-released with hormones. Chromogranin fragments (WE-14, catestatin, vasostatin) have independent bioactivity. Multiple assays exist with varying cutoffs.

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PSA (Prostate-Specific Antigen)

ID: BIO-012 | | Length | 712 amino acids |

| Category | Biomarker Peptides |

Structure

Sequence: 439 amino acids (precursor processed to multiple fragments) belongs to the Biomarker Peptides class of peptides. Its structure and properties make it suitable for various research and therapeutic applications.

Applications

Sequence: 439 amino acids (precursor processed to multiple fragments) has been studied for its potential applications in:

• Biomedical research
• Drug discovery
• Diagnostic applications
• Therapeutic development

References

• Source: biomarker-peptides.md
• Database: Wikipept Peptide Database