**Sequence:** 51 amino acids (A-chain 21 + B-chain 30, disulfide-linked)
**Sequence:** 31 amino acids (connecting peptide of proinsulin)
Overview
Sequence: 51 amino acids (A-chain 21 + B-chain 30, disulfide-linked) is a peptide compound with applications in research and therapeutics. Sequence: 31 amino acids (connecting peptide of proinsulin)
Chemical Identity
| Property | Value |
|---|---|
| Name | Sequence: 51 amino acids (A-chain 21 + B-chain 30, disulfide-linked) |
| Sequence | Disease: Diabetes mellitus (type 1, type 2); insulinoma; metabolic syndrome; insulin resistance; PCOS |
Clinical Use: Insulinoma diagnosis (72h fast); C-peptide-based assessment of endogenous insulin; HOMA-IR calculation; insulin resistance screening
Cutoff Values: Fasting insulin: 2–20 μIU/mL (normal). HOMA-IR = (fasting insulin × fasting glucose)/405; >2.5 suggests insulin resistance. Insulinoma: insulin >3 μIU/mL during hypoglycemia (glucose <45 mg/dL) at 72h fast.
Exogenous insulin assays must distinguish from endogenous. Insulin analogs (lispro, glargine) show variable cross-reactivity. Proinsulin measured separately in insulinoma workup. Use C-peptide to distinguish endogenous vs. exogenous hyperinsulinemia.
C-Peptide
ID: BIO-020 | | Length | 773 amino acids |
| Category | Biomarker Peptides |
Structure
Sequence: 51 amino acids (A-chain 21 + B-chain 30, disulfide-linked) belongs to the Biomarker Peptides class of peptides. Its structure and properties make it suitable for various research and therapeutic applications.
Applications
Sequence: 51 amino acids (A-chain 21 + B-chain 30, disulfide-linked) has been studied for its potential applications in:
- Biomedical research
- Drug discovery
- Diagnostic applications
- Therapeutic development
References
- Source: biomarker-peptides.md
- Database: Wikipept Peptide Database
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