**Sequence:** 84 amino acids (full-length PTH); active fragment PTH(1-34)

Overview

Sequence: 84 amino acids (full-length PTH); active fragment PTH(1-34) is a peptide compound with applications in research and therapeutics. Sequence: G-17 (17 amino acids, major circulating form); G-34 (big gastrin)

Chemical Identity

Property	Value
Name	Sequence: 84 amino acids (full-length PTH); active fragment PTH(1-34)
Sequence	Disease: Primary hyperparathyroidism; secondary hyperparathyroidism (CKD); hypoparathyroidism; vitamin D deficiency

Clinical Use: Differential diagnosis of hypercalcemia; monitoring CKD-MBD; intraoperative parathyroid localization; guiding parathyroidectomy

Cutoff Values: Intact PTH: 10–65 pg/mL (normal, assay-dependent). Primary HPT: elevated or inappropriately normal with hypercalcemia. CKD stage 3–5: KDIGO targets 2–9× upper normal. Intraoperative: >50% drop at 10 min predicts successful removal.

Calcium homeostasis regulator. Intact PTH assay (1-84) standard; PTH(7-84) fragments detected by some assays. ioPTH monitoring during parathyroidectomy guides surgical completeness. Two-site immunoradiometric/immunochemiluminometric assays (IRMA/ICMA).

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Gastrin

ID: BIO-018 | | Length | 807 amino acids |

| Category | Biomarker Peptides |

Structure

Sequence: 84 amino acids (full-length PTH); active fragment PTH(1-34) belongs to the Biomarker Peptides class of peptides. Its structure and properties make it suitable for various research and therapeutic applications.

Applications

Sequence: 84 amino acids (full-length PTH); active fragment PTH(1-34) has been studied for its potential applications in:

• Biomedical research
• Drug discovery
• Diagnostic applications
• Therapeutic development

References

• Source: biomarker-peptides.md
• Database: Wikipept Peptide Database