Insect Peptides intermediate
Spidroin I (Nephila): Oligopeptide Research Reference
Spidroin I (Nephila), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
insect-peptides peptide oligopeptide
Overview
Spidroin I (Nephila) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Nephila clavipes (golden orb-weaver spider).
Structure
| Property | Value |
|---|---|
| Name | Spidroin I (Nephila) |
| Sequence | Repetitive (AAAA)n and (GA)n motifs with GGX and poly-A repeats |
| Length | ~3500 amino acids |
| Molecular Weight | 250000-350000 Da |
| Source | Nephila clavipes (golden orb-weaver spider) |
| Category | Silk Protein / Structural |
Mechanism of Action
Self-assembles into beta-sheet nanocrystals embedded in amorphous glycine-rich matrix
Bioactivity
Superior tensile strength (~1.1 GPa), extensibility (~27%), toughness
Therapeutic Potential
Biodegradable sutures, tissue engineering scaffolds, body armor, biomaterials
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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