Insect Peptides intermediate
Spidroin II (Nephila): Oligopeptide Research Reference
Spidroin II (Nephila), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
By Encyclopeptide Editorial | 1 min read
insect-peptides peptide oligopeptide
Overview
Spidroin II (Nephila) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Nephila clavipes (golden orb-weaver spider).
Structure
| Property | Value |
|---|---|
| Name | Spidroin II (Nephila) |
| Sequence | Repetitive (GPGXX)n and (AAAA)n motifs with proline-containing elastic modules |
| Length | ~3500 amino acids |
| Molecular Weight | 250000-350000 Da |
| Source | Nephila clavipes (golden orb-weaver spider) |
| Category | Count |
Mechanism of Action
Beta-sheet crystallites with proline-containing elastic segments providing extensibility
Bioactivity
Enhanced extensibility compared to Spidroin I, supercontraction properties
Therapeutic Potential
Elastic biomaterials, drug delivery systems, flexible scaffolds
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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