Tetrodotoxin (TTX): Peptide Toxin in Pharmacology Reference
Tetrodotoxin (TTX), a bioactive peptide compound with documented applications in biomedical research, pharmacological studies, and therapeutic development
Overview
Tetrodotoxin (TTX) is a bioactive peptide with well-characterized properties and therapeutic applications. It is derived from Takifugu (pufferfish), Taricha (newts).
Structure
| Property | Value |
|---|---|
| Name | Tetrodotoxin (TTX) |
| Length | N/A (small molecule) | | Molecular Weight | 319.27 Da | | Source | Takifugu (pufferfish), Taricha (newts) | | Category | Marine Toxin / Analgesic |
Mechanism of Action
Pore blocker - binds to site 1 of Nav channels, blocking ion conductance
Bioactivity
Neurotoxin, analgesic properties
Therapeutic Potential
Pain management, cancer pain, opioid-sparing analgesic
References
- Wikipept Peptide Database
- Primary literature (see individual entries)
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