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Peptide Classification System

By Length

Classification Residue Count Examples MW Range (Da)
Dipeptide 2 Carnosine, Anserine 200–300
Tripeptide 3 Glutathione, thyrotropin-releasing hormone 300–500
Tetrapeptide 4 Angiotensin II (fragment), kyotorphin 400–600
Pentapeptide 5 Enkephalins, tuftsin 500–700
Hexapeptide 6 ACE inhibitors (fragment) 600–800
Heptapeptide 7 Substance P (fragment) 700–900
Octapeptide 8 Vasopressin, oxytocin (cyclic) 800–1100
Nonapeptide 9 Oxytocin, vasopressin 1000–1200

By Function

Neuropeptides

Signaling molecules in the nervous system. Include endorphins, enkephalins, substance P, and neuropeptide Y.

Hormonal Peptides

Regulate physiological processes. Include insulin, glucagon, oxytocin, and growth hormone-releasing hormone.

Antimicrobial Peptides

Innate immune defense. Include defensins, cathelicidins, and magainins.

Antioxidant Peptides

Protect against oxidative stress. Include glutathione, carnosine, and erogothioneine.