Therapeutic Peptides intermediate
Peptide Neurological Therapeutics
Therapeutic peptides targeting neurological conditions including pain, neurodegenerative diseases, and psychiatric disorders.
By Encyclopeptide Editorial | 1 min read
neurological therapeutic pain neurodegeneration CNS
Overview
Peptide therapeutics for neurological conditions face unique challenges including blood-brain barrier penetration and CNS stability.
Major Neurological Peptides
| Drug | Target | Indication |
|---|---|---|
| Ziconotide | N-type Ca2+ | Severe chronic pain |
| Lasmiditan | 5-HT1F agonist | Acute migraine |
| Erenumab | CGRP receptor | Migraine prevention |
Blood-Brain Barrier Strategies
- Intrathecal delivery: Direct CSF administration
- BBB-shuttle peptides: Transferrin receptor targeting
- Nasal delivery: Nose-to-brain pathway
- Focused ultrasound: Transient BBB opening
Chemical Identity
| Property | Value |
|---|---|
| Name | Peptide Neurological Therapeutics |
| Category | Therapeutic Peptides |
References
- Encyclopeptide Database. “Peptide Neurological Therapeutics” monograph. encyclopeptide.com.
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